Inhibition of tryptophan metabolism by oestrogens in the rat: a factor in the aetiology
نویسنده
چکیده
David A. Bender and Lena Totoe British Journal of Nutrition / Volume 51 / Issue 02 / March 1984, pp 219 224 DOI: 10.1079/BJN19840026, Published online: 09 March 2007 Link to this article: http://journals.cambridge.org/abstract_S0007114584000271 How to cite this article: David A. Bender and Lena Totoe (1984). Inhibition of tryptophan metabolism by oestrogens in the rat: a factor in the aetiology of pellagra. British Journal of Nutrition,51, pp 219224 doi:10.1079/BJN19840026 Request Permissions : Click here
منابع مشابه
Inhibition of tryptophan metabolism by oestrogens in the rat: a factor in the aetiology of pellagra.
The effect of the administration of oestrone sulphate on tryptophan metabolism has been assessed in rats in order to determine whether and to what extent inhibition of tryptophan metabolism by oestrogens may be a factor in the aetiology of pellagra, and might explain the reported twofold excess of females over males in many outbreaks of pellagra. Feeding ovariectomized rats for 1 week on a diet...
متن کاملEffects of oestradiol and vitamin B6 on tryptophan metabolism in the rat: implications for the interpretation of the tryptophan load test for vitamin B6 nutritional status.
1. The effects of the administration of oestradiol and vitamin B, on tryptophan metabolism in the rat have been assessed by measurement of the release of 14C0, from [14C]tryptophan, in vivo, in order to determine whether, and to what extent, the abnormalities of tryptophan metabolism that are associated with oestrogen administration can be attributed to drug-induced vitamin B, deficiency or dep...
متن کاملEffects of oestrogen administration on vitamin B6 and tryptophan metabolism in the rat.
1. In order to assess the effects of oestrogens on the metabolism of tryptophan and vitamin B6, ovariectomized rats have been maintained on diets providing known amounts of tryptophan, nicotinamide and vitamin B6. They received oestrone sulphate, 210 micrograms/kg body-wt per d, either incorporated in the diet for 8 weeks, or by daily intraperitoneal injection for periods of 1-3 d. 2. Oestrone ...
متن کاملVoltammetric determination of acetaminophen and tryptophan using a graphite screen printed electrode modified with functionalized graphene oxide nanosheets within a Fe3O4@SiO2 nanocomposite
A high sensitive electrochemical nanostructure sensor based on graphene oxide/Fe3O4@SiO2 nanocomposite modified graphite screen printed electrode (GO/Fe3O4@SiO2/SPE) has been developed for trace analysis of acetaminophen. The electrochemical study of the modified electrode, as well as its efficiency for simultaneous voltammetric oxidation of acetaminophen and tryptophan is described. Compared w...
متن کاملEffect of ovarian hormones and oral contraceptives on tryptophan metabolism
Women using oral contraceptives of the combined oestrogen-progestogen type excrete elevated levels of a number of metabolites of the tryptophan-nicotinic acid ribonucleotide metabolic pathway in urine collected after an oral dose of the amino acid. Increased excretions of Nl-methylnicotinamide reflect an enhanced capacity for the conversion of Ltryptophan to nicotinic acid derivatives, although...
متن کامل